In the transcript, the speaker discusses various ways to improve productivity in a work-from-home setup. They emphasize the importance of setting boundaries to separate work and personal life, such as designating a specific workspace. Prioritizing tasks, establishing a routine, and taking breaks are highlighted as crucial for maintaining focus and avoiding burnout. The speaker also recommends using productivity tools and techniques like time blocking and the Pomodoro technique to enhance efficiency. Additionally, fostering open communication with colleagues through virtual meetings and utilizing collaboration platforms is suggested to stay connected and engaged while working remotely. Finally, the speaker emphasizes the significance of self-care, stress management, and finding a healthy work-life balance to ensure long-term productivity and well-being.